![]() ![]() Creatinine was measured in parallel using the Nova StatSensor Xpress Creatinine analyzer and the Vitros 5,1FS (Ortho Clinical Diagnostics, Inc, Rochester, USA), which served as reference standard. The StatSensor Xpress Creatinine (Nova Biomedical Cooperation, Waltham, MA, USA) point of care analyzer was evaluated for its diagnostic performance in indicating drug therapy change. A point of care instrument to measure creatinine would be useful for patients monitoring in resource-limited settings, where more instruments that are sophisticated are not available. Kosack, Cara Simone de Kieviet, Wim Bayrak, Kubra Milovic, Anastacija Page, Anne LaureĬreatinine is a parameter that is required to monitor renal function and is important to follow in patients under treatment with potentially toxic renal drugs, such as the anti-HIV drug Tenofovir. PMID:25886375Įvaluation of the Nova StatSensor® Xpress(TM) Creatinine point-of-care handheld analyzer. The analyzer was found sufficiently accurate for detecting pathological values in patients (age >10 year) and can be used with a moderate risk of misclassification. The Nova StatSensor Xpress Creatinine analyzers showed acceptable to good results in terms of repeatability, inter-device reproducibility and between-run reproducibility over time using quality control reagents. The Bland-Altman analysis in high pathological specimens suggests that the Nova StatSensor Xpress Creatinine test tends to underestimate high creatinine values (i.e., >600 µmol/L). The turnaround time (median, interquartile range ) of the POCT group was shorter than that of the CLT group (14, 12-19 versus 55, 45-69 minutes P 10 kPa during CPB (r = −0.59, p 600 µmol/L). All of the basic characteristics were similar in the 2 groups. The total 2323 patients were randomly assigned to the POCT group (n = 1167) or to the CLT group (n = 1156). Primary and secondary end point was turnaround time and door-to-clinical-decision time. A POCT chemistry analyzer (Piccolo Abaxis, Inc, Union City, Calif), which is able to test liver panel, renal panel, pancreas enzymes, lipid panel, electrolytes, and blood gases, was set up in each ED. We randomly assigned patients to POCT or CLT stratified by the Emergency Severity Index. This was a randomized controlled multicenter trial in the emergency departments (EDs) of 5 academic teaching hospitals. Our study compared clinical decision time between patients managed with a point-of-care chemistry test (POCT) and patients managed with the traditional central laboratory test (CLT). Lee, Eui Jung Shin, Sang Do Song, Kyoung Jun Kim, Seong Chun Cho, Jin Seong Lee, Seung Chul Park, Ju Ok Cha, Won Chul A point-of-care chemistry test for reduction of turnaround and clinical decision time. ![]()
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